2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. DNA Alkylator/Crosslinker
  5. DNA Alkylator/Crosslinker Antagonist

DNA Alkylator/Crosslinker Antagonist

DNA Alkylator/Crosslinker Antagonist (1):

Cat. No. Product Name Effect Purity
  • HY-129241
    AGX51
    		Antagonist 99.33%
    AGX51 is the first-in-class pan-Id (inhibitors of DNA-binding/differentiation proteins) antagonist and degrader. AGX51 inhibits Id1-E47 interaction, leading to ubiquitin-mediated degradation of Ids, cell growth arrest, and viability reduction. AGX51 can inhibit TNBC and has an IC50 of about 25 nM. AGX51 can be used in cancer research.